New approaches to the visualization, quantification and explanation of acid-induced water loss from Ca-alginate hydrogel beads.

@article{Doumche2004NewAT,
  title={New approaches to the visualization, quantification and explanation of acid-induced water loss from Ca-alginate hydrogel beads.},
  author={B Doum{\`e}che and Markus Kueppers and Siegfried Stapf and Bernhard Bl{\"u}mich and Winfried Hartmeier and Marion Ansorge-Schumacher},
  journal={Journal of microencapsulation},
  year={2004},
  volume={21 5},
  pages={565-73}
}
The water loss of Ca-alginate hydrogels at pHs below 4.0 was visualized with 1HNMR-imaging by covering a single alginate bead with cyclohexane-d12 in a specially equipped NMR-tube and adding propionic acid at defined concentrations. The exact amount of water expelled from the beads was calculated from their weight loss and correlated with the acid concentrations and pHs within the hydrogel matrix. The maximum water loss of 52% (w/w) occurred at pH 1.0, while only 5% (w/w) of the initial water… CONTINUE READING