New approaches to the treatment of giardiasis.

  title={New approaches to the treatment of giardiasis.},
  author={Noa Tejman-Yarden and Lars Eckmann},
  journal={Current opinion in infectious diseases},
  volume={24 5},
PURPOSE OF REVIEW Giardiasis is one of the most common causes of diarrheal disease worldwide, yet existing antimicrobial therapies are not always effective and drug resistance occurs in vivo and in vitro. The review focuses on recent advances in the development of new antigiardial drug candidates. RECENT FINDINGS Modification of existing drug leads is a major strategy to develop new high-potency drugs. Complex derivatives of 5-nitroimidazole, the core structure of the most commonly used… CONTINUE READING