New approaches to the treatment of dense deposit disease.

  title={New approaches to the treatment of dense deposit disease.},
  author={Richard J H Smith and Jessy John Alexander and Paul N. Barlow and Marina Botto and Thomas L Cassavant and H. Terence Cook and Santiago Rodr{\'i}guez de C{\'o}rdoba and Gregory S. Hageman and T Sakari Jokiranta and William J. Kimberling and John D. Lambris and Lynne Lanning and Vicki Levidiotis and Christoph Licht and Hans U. Lutz and Seppo Meri and Matthew C Pickering and Richard J Quigg and Angelique L. W. M. M. Rops and David J Salant and Sanjeev Sethi and Joshua M Thurman and Hope F Tully and Sean P Tully and Johan van der Vlag and P. Duane Walker and Reinhard Wuerzner and Peter F Zipfel},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={18 9},
The development of clinical treatment protocols usually relies on evidence-based guidelines that focus on randomized, controlled trials. For rare renal diseases, such stringent requirements can represent a significant challenge. Dense deposit disease (DDD; also known as membranoproliferative glomerulonephritis type II) is a prototypical rare disease. It affects only two to three people per million and leads to renal failure within 10 yr in 50% of affected children. On the basis of… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 77 references

A descriptive study of individuals with membranoproliferative glomerulonephritis.

Nephrology nursing journal : journal of the American Nephrology Nurses' Association • 2007

Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 2007


C Licht, A Weyersberg, +7 authors B Hoppe
J Am Soc Nephrol • 2007

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