New approaches to the management of COPD.

  title={New approaches to the management of COPD.},
  author={Rob A Stockley},
  volume={117 2 Suppl},
Airflow limitation in COPD is a result partially of bronchospasm, but it is also caused by a reduction in airway caliber, the number of small airways, airway collapse because of loss of connective tissue support, excess mucus in the airways, and edema of the airway wall. Structural changes also occur because of long-term destruction of interstitial connective tissue, including elastin. Therefore, in addition to the traditional aim of reversing bronchospasm with bronchodilators, disease… CONTINUE READING
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