New approaches to peptide synthesis with the help of trypsin.

Abstract

Picolyl esters of amino acids are suitable inverse substrates for trypsin. These esters can be used for peptide synthesis catalyzed by trypsin. Study of hydrolysis of non-specific substrates for trypsin permits to conclude, that hydrogen band in P'2 subsite is very important for their reactivity. Carboxamido methyl esters (CAM-esters) are the most suitable… (More)

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Cite this paper

@article{YuV1991NewAT, title={New approaches to peptide synthesis with the help of trypsin.}, author={Mitin YuV and N P Zapevalova and Gorbunova EYu}, journal={Biomedica biochimica acta}, year={1991}, volume={50 10-11}, pages={S74-9} }