New antiepileptic drugs

@article{Harden1994NewAD,
  title={New antiepileptic drugs},
  author={Cynthia Harden},
  journal={Neurology},
  year={1994},
  volume={44},
  pages={787 - 787}
}
  • C. Harden
  • Published 1 May 1994
  • Medicine
  • Neurology
Antiepileptic drugs (AEDs) were first developed by empiric drug testing, without any basic understanding of epileptic processes. Bromide salts were used for epilepsy in the last century with the notion that this medicine would suppress sexual desire, which-according t o prevailing scientific thought in the 1860s-would in turn suppress seizure activity.l However, the sedative action of bromides correlated with seizure reduction, which led to the discovery in 1912 of another sedative with… 
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