New anticoagulants and their potential impact on the treatment of thromboembolic disease.

  • Jack Ansell
  • Published 2004 in Current hematology reports


Traditional anticoagulants have drawbacks that make them complex to manage, limit their usefulness, and increase the possibility of adverse events. New anticoagulants are being developed that directly target a single coagulation factor. The agents have improved pharmacokinetics and pharmacodynamics and may not need coagulation monitoring. In addition, many… (More)