New anti-inflammatory triterpene from the root of Ricinus communis

  title={New anti-inflammatory triterpene from the root of Ricinus communis},
  author={Pooja Srivastava and Jyotshna and Namita Gupta and Anil Kumar Maurya and Karuna Shanker},
  journal={Natural Product Research},
  pages={306 - 311}
Liquid–liquid partitioning of Ricinus communis root methanol extract resulted in enrichment of compounds. Purification of the n-hexane fraction led to the isolation and characterisation of two triterpenes: one known compound lupeol (1) and a new diketone pentacyclic triterpene named as erandone (urs-6-ene-3,16-dione) (2), from the plant. Their structures were determined by various spectroscopic techniques. Crude methanolic, enriched n-hexane fraction and isolates at doses 100 mg/kg p.o… 
Antibacterial Triterpenoids from the Bark of Sonneratia alba (Lythraceae)
The new lupane-type triterpenoid, 3β-hydroxy-lup-9, 12-diene, 28-oic acid, along with two known lupeol and lupan-3p-ol, were isolated from the bark of Sonnetaria alba and exhibited antibacterial activity against Gram-positive bacteria.
Elatumic Acid: A New Ursolic Acid Congener from Omphalocarpum elatum Miers (Sapotaceae)
A new triterpene diastereomer of the previously reported 3β,6β,19α-trihydroxy-urs-12-en- 28-oic acid-24-carboxylic acid methyl ester was obtained from the stem bark of Omphalocarpum elatum Miers along with α-amyrin acetate, showing weak antibacterial activity against E. pneumoniae and moderate cytotoxicity against CCRF-CEM.
Structural and phytochemical investigation of the leaves of Ricinus communis
The phytochemical analysis of leaf extracts using UHPLC-HRMS and GC-MS confirmed the results of the histochemical tests and, among other metabolites, the flavonoids rutin, isoquercetin, and nicotiflorin, as well as the toxic alkaloid ricinine were detected.
Phytochemical and Pharmacological Investigations of Ricinus communis Linn.
The aim of present article is to explore the chemical constituents, their structures and medicinal importance of Ricinus communis.
Therapeutic role of Ricinus communis L. and its bioactive compounds in disease prevention and treatment
Considering its wide variety of phytochemicals, its pharmacological activity and the subsequent clinical trials, R. communis could be a good candidate for discovering novel complementary drugs.
Microwave-assisted single step cinnamic acid derivatization to mimic vanillin isomer and their cytotoxic potential.
The present study gives a very reliable and simple method for isolation of HMB and cinnamic acid modification that efficiently reduces the reaction time and proves to be friendly with environment.
Simultaneous analytical efficiency evaluation using HPTLC method for analysis of syringicacid and vanillic acid and their anti-oxidant capacity from methanol extract of Ricinus communis Linn. and Euphorbia hirta Linn.
A simple, rapid, reliable and accessible HPTLC technique has been established for concurrent quantification of phenolic compounds (syringic acid and vanillic acid) and evaluation of their anti-oxidant capacity and significant free radical scavenging capacity against DPPH generated free radicals are obtained.
Synthesis of Gold Nanoparticles (AuNPs) Using Ricinus communis Leaf Ethanol Extract, Their Characterization, and Biological Applications
RcExt was safe while RcExt-AuNPs harmful to red blood cells (RBCs) and showed inhibitory effects on splenic cells irrespective of dose, as well as showing comparatively more antimicrobial activity.
Potential Anti-Arthritic Agents From Indian Medicinal Plants
The need to explore potential chemical moieties from unexploited plants in arthritic management along with the mechanism of action through which they would act, remain to be studied is reflected.
Separation and quantification of lupeol in Hygrophila schulli by high-performance thin-layer chromatography
Lupeol is the main active constituent of Hygrophila schulli (HS) plant. A simple, reliable and reproducible method of quantification is needed for the quality control of HS. Therefore,


Three new triterpenes from the resinous bark of Protium kleinii and their antinociceptive activity
Three novel pentacyclic triterpenes have been isolated from the resin of Protium kleinii and their structures elucidated by NMR spectroscopy as 3-oxo-11b,16b-dihydroxy-urs-12-ene (1),
Effects of antiinflammatory triterpenes isolated from Leptadenia hastata latex on Keratinocyte Proliferation
Results prove that the triterpenes play a pivotal role in the topical antiinflammatory effect of this latex.
Antidiabetic activity of 50% ethanolic extract of Ricinus communis and its purified fractions.
Anti-inflammatory and free radical scavenging activity of Ricinus communis root extract.
Triterpenos da resina de Protium heptaphyllum March (B0urseraceae): caracterização em misturas binárias
Eight triterpenes, maniladiol, breine, ursa-9(11):12-dien-3b-ol, oleana-9(11):12-dien-3b-ol, 3a-hydroxy-tirucalla-8,24-dien-21-oic acid, 3a-hydroxy-tirucalla-7,24-dien-21-oic, a and b amyrines were
Antihepatotoxic actions of Formosan plant drugs.
Acyl lupeols from cnidoscolus vitifolius
Antifertility effects of Ricinus communis (Linn) on rats
Reversibility tests showed that the antifertility effect of Ricinus communis was completely reversible on withdrawal of the drug.