New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp.

  title={New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp.},
  author={Lin Du and Dehai Li and Tianjiao Zhu and Sheng-xin Cai and Fengping Wang and Xiang Xiao and Qianqun Gu},

Alkaloids from a deep ocean sediment-derived fungus Penicillium sp. and their antitumor activities

The results indicate that the distinct substitutions on the imidazole ring significantly influence the cytotoxicity of the meleagrin alkaloids.

Four New Chloro-Eremophilane Sesquiterpenes from an Antarctic Deep-Sea Derived Fungus, Penicillium sp. PR19N-1

A new chloro-trinoreremophilane sesquiterpene 1, three new chlorinated eremophilane sesquiterpenes 2–4, together with a known compound, eremofortine C (5), were isolated from an Antarctic deep-sea

Sterigmatocystins from the deep-sea-derived fungus Aspergillus versicolor

Three new sterigmatocystin derivatives were isolated from the deep-sea-derived fungus Aspergillus versicolor and the structures of the new compounds were elucidated by spectroscopic methods.

Roquefortine J, a novel roquefortine alkaloid, from the deep-sea-derived fungus Penicillium granulatum MCCC 3A00475

The planar structure of 1 was established mainly on the basis of extensive analysis of its 1D, 2D NMR, and HRESIMS spectra, which determined the absolute configuration of 1 by comparison of the calculated and experimental electronic circular dichroism spectra.

Penibruguieramine A, a novel pyrrolizidine alkaloid from the endophytic fungus Penicillium sp. GD6 associated with Chinese mangrove Bruguiera gymnorrhiza.

The absolute configuration of penibruguieramine A was established by TDDFT ECD calculations of the vacuum and solution conformers, exploiting the transitions of the lactam chromophore.

Penicyclones A-E, Antibacterial Polyketides from the Deep-Sea-Derived Fungus Penicillium sp. F23-2.

Five new ambuic acid analogues, penicyclones A-E (1-5), were isolated from the extract of the deep-sea-derived fungus Penicillium sp. F23-2. The structures including the absolute configurations were

Sorbicillamines A-E, nitrogen-containing sorbicillinoids from the deep-sea-derived fungus Penicillium sp. F23-2.

Five new nitrogen-containing sorbicillinoids named sorbicillamines A-E (1-5) were isolated from an agitated culture of the deep-sea-derived fungus Penicillium sp. F23-2, which has previously produced

Cladosins A-E, hybrid polyketides from a deep-sea-derived fungus, Cladosporium sphaerospermum.

Five new fungal hybrid polyketides, cladosins A-D (1-4), as well as the biogenetically related cladosin E (5), were isolated from the deep-sea-derived fungus Cladosporium sphaerospermum 2005-01-E3 and elucidated through a combination of spectroscopic data, chemical conversion, and both Mosher's and Marfey's methods for stereochemical assignment.



Isolation of a New Indole Alkaloid, Roquefortine D, from the Cultures of Penicillium roqueforti

Previously, we1-3) isolated three indole alkaloids, roquefortine A, B and C, from the cultures of Penicilli um roqueforti, and made clear the structures of those alkaloids. Recently, we have isolated

Studies on Fungal Products. VII. The Structures of Meleagrin and 9-O-p-Bromobenzoylmeleagrin

The structure of meleagrin (1), isolated from Penicillium meleagrinum, was determined by X-ray crystallographic analysis of 9-O-p-bromobenzoylmeleagrin (7) monohydrate. The crystal structure of 7

Roquefortine E, a diketopiperazine from an Australian isolate of Gymnoascus reessii.

The new isoprenylated diketopiperazine roquefortine E has been isolated from an Australian soil isolate of the ascomycete Gymnoascus reessii and all structures were assigned by detailed spectroscopic analysis.

Biosynthesis of Prenylated Alkaloids Derived from Tryptophan

The biosynthesis of prenylated indole alkaloids and related natural substances derived from tryptophan is reviewed and the groups selected based on their structural and biogenetic similarities are examined.

Roquefortine, an intermediate in the biosynthesis of oxaline in cultures of Penicillium oxalicum

The incorporation of (2RS)-[indole-2-13C, 2-15N]tryptophan into both roquefortine and oxaline, and the efficient conversion of roquefortine into oxaline, defines a biosynthetic pathway by which N-14

Roquefortine/Oxaline Biosynthesis Pathway Metabolites in Penicillium ser. Corymbifera: In Planta Production and Implications for Competitive Fitness

The deposition of roquefortine/oxaline pathway metabolites as an extracellular nitrogen reserve for uptake and metabolism into growing mycelia and the synergistic role of terrestric acid and other Corymbifera secondary metabolites in enhancing the competitive fitness of Corymbifiera species in planta are proposed.