New agents for sedation in the intensive care unit.

  title={New agents for sedation in the intensive care unit.},
  author={Mervyn M Maze and C Scarfini and Franco Cavaliere},
  journal={Critical care clinics},
  volume={17 4},
Several advances are likely to benefit the ICU patient requiring sedation, analgesia, and anxiolysis. The cooperative sedation induced by dexmedetomidine is a unique and valuable state that allows patients to be aroused easily and interferes little with ventilation. Remifentanil is the prototype of short-acting drugs, providing fast onset and offset; its relatively high cost may be balanced by limiting the risk for long-lasting respiratory depression. Lorazepam seems to be finding more… CONTINUE READING


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