New advances in models and strategies for developing anti-obesity drugs.

  title={New advances in models and strategies for developing anti-obesity drugs.},
  author={Gilbert Won Kim and Jieru Egeria Lin and Erik Scott Blomain and Scott A. Waldman},
  journal={Expert opinion on drug discovery},
  volume={8 6},
INTRODUCTION Obesity is a worldwide pandemic. Obesity-related health and economic costs are staggering. Existing strategies to combat obesity through lifestyle improvements and medical intervention have had limited success. Pharmacotherapy, in combination with lifestyle modification, may play a vital role in reversing the disease burden. However, past and current weight-loss medications have had serious safety risks, notably cardiovascular and psychiatric events. AREAS COVERED The authors… CONTINUE READING
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