New Submonomers for Poly N-Substituted Glycines ( Peptoids )

  title={New Submonomers for Poly N-Substituted Glycines ( Peptoids )},
  author={Tetsuo Uno and Eric Beausoleil and Richard A. Goldsmith and Barry H. Levine and Ronald N. Zuckermann},
Received lO November 1998; revised 17 December 1998; accepted 18 December 1998 Abstract: Five protected submonomers for peptoid synthesis were prepared, including N~-BOC-tryptamine, O-t-butyl tyramine, PMC-guanidino-propylamine, 6-amino-6-deoxyD-galactopyranose diacetonide, and 5-amino-2,2-dimethyl-l,3-dioxane. The first three mimic natural aminoacid sidechains i.e. tryptophan, tyrosine, and arginine, while the last two provide hydrophilic sidechains. These submonomers were successfully used… CONTINUE READING


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