New Strategies for Stem Cell Mobilization

  title={New Strategies for Stem Cell Mobilization},
  author={Roberto Massimo Lemoli},
  booktitle={Mediterranean journal of hematology and infectious diseases},
Mobilized peripheral blood (PB) is widely used as source of stem cells (PBSCs) for autologous stem cell transplantation (ASCT). The use of cytokines, alone or in combination with chemotherapy (chemomobilization), is the most common strategy applied to mobilize and collect PBSCs. However, a significant proportion of cancer patients fail to mobilize enough PBSCs to proceed to ASCT. Plerixafor is a small molecule that reversibly and transiently disrupts the interaction between the chemokine… CONTINUE READING


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