New Rp-hplc Method Development and Validation Determination for Estimation of Duloxetine Hcl in Enteric Coated Capsules

  • Rahul Dadaroji, Jawarkar, M. Prakash, Bibin Mathew
  • Published 2003


A simple, selective, rapid, and precise reverse phase HPLC method has been developed for the simultaneous estimation of duloxetine HCL in enteric coated capsules. An X Terra RP, C-8 column (4.6x150mm) was used for the separation. The mobile phase was acetonitrile: phosphate buffer (65:35%v/v) (Ph5.3) at a flow rate of 1.0 ml/min with detection at 230nm. The… (More)


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