New Perspectives in the Renin-Angiotensin-Aldosterone System (RAAS) III: Endogenous Inhibition of Angiotensin Converting Enzyme (ACE) Provides Protection against Cardiovascular Diseases

Abstract

ACE inhibitor drugs decrease mortality by up to one-fifth in cardiovascular patients. Surprisingly, there are reports dating back to 1979 suggesting the existence of endogenous ACE inhibitors. Here we investigated the clinical significance of this potential endogenous ACE inhibition. ACE concentration and activity was measured in patient's serum samples (n… (More)
DOI: 10.1371/journal.pone.0093719

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@inproceedings{Fagyas2014NewPI, title={New Perspectives in the Renin-Angiotensin-Aldosterone System (RAAS) III: Endogenous Inhibition of Angiotensin Converting Enzyme (ACE) Provides Protection against Cardiovascular Diseases}, author={Mikl{\'o}s Fagyas and Katalin {\'U}ri and Ivetta M{\'a}nyin{\'e} Siket and Andrea Darag{\'o} and Judit Bocz{\'a}n and Emese B{\'a}nyai and Istvan Edes and Zolt{\'a}n Papp and Attila T{\'o}th}, booktitle={PloS one}, year={2014} }