New Oral Anticoagulants

@article{Poulsen2012NewOA,
  title={New Oral Anticoagulants},
  author={Dr Birgitte Klindt Poulsen and Erik Lerkevang Grove and Steen Elkjaer Husted},
  journal={Drugs},
  year={2012},
  volume={72},
  pages={1739-1753}
}
Oral anticoagulant therapy (OAT) is widely used to prevent and treat thromboembolic events. Traditionally, warfarin has been the drug of choice and, indeed, this drug is effective and provides a more than 60% reduction in stroke risk in patients with atrial fibrillation. However, OAT entails an increased bleeding risk, and management of this is challenging. Among other things, new oral anticoagulant drugs offer fixed dosing, more predictable pharmacokinetics and fewer interactions with drugs… CONTINUE READING
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