New OprM structure highlighting the nature of the N-terminal anchor

Abstract

Among the different mechanisms used by bacteria to resist antibiotics, active efflux plays a major role. In Gram-negative bacteria, active efflux is carried out by tripartite efflux pumps that form a macromolecular assembly spanning both membranes of the cellular wall. At the outer membrane level, a well-conserved outer membrane factor (OMF) protein acts as an… (More)
DOI: 10.3389/fmicb.2015.00667

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Cite this paper

@inproceedings{Monlezun2015NewOS, title={New OprM structure highlighting the nature of the N-terminal anchor}, author={Laura Monlezun and Gilles Phan and Houssain Benabdelhak and Marie-Bernard Lascombe and V{\'e}ronique Y. N. Engu{\'e}n{\'e} and Martin Picard and Isabelle Broutin}, booktitle={Front. Microbiol.}, year={2015} }