New-Onset Headache in Patients With Autoimmune Encephalitis Is Associated With anti-NMDA-Receptor Antibodies.

@article{Schankin2016NewOnsetHI,
  title={New-Onset Headache in Patients With Autoimmune Encephalitis Is Associated With anti-NMDA-Receptor Antibodies.},
  author={Christoph Schankin and Fabian K{\"a}stele and Lisa Ann Gerdes and Tobias Winkler and Endy Csanadi and Tobias H{\"o}gen and Hannah Pellkofer and Walter Paulus and Tania Kuempfel and Andreas M. Straube},
  journal={Headache},
  year={2016},
  volume={56 6},
  pages={
          995-1003
        }
}
OBJECTIVE We tested the hypotheses (i) that autoimmune encephalitis is associated with new-onset headache, and (ii) that the occurrence of headache is associated with the presence of anti-N-methyl-D-aspartate (NMDA)-receptor antibodies. BACKGROUND Autoimmune encephalitis presents with cognitive dysfunction as well as neuro-psychiatric symptoms. Its pathophysiology might involve antibody-mediated dysfunction of the glutamatergic system as indicated by the presence of anti-NMDA-receptor… CONTINUE READING
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