New Nomenclature for Chromatin-Modifying Enzymes

@article{Allis2007NewNF,
  title={New Nomenclature for Chromatin-Modifying Enzymes},
  author={C. David Allis and Shelley L. Berger and Jacques C{\^o}t{\'e} and Sharon Y. R. Dent and Thomas Jenuwien and Tony Kouzarides and Lorraine Pillus and Danny Reinberg and Yang Shi and Ramin Shiekhattar and Ali Shilatifard and Jerry L. Workman and Yi Zhang},
  journal={Cell},
  year={2007},
  volume={131},
  pages={633-636}
}

Tables from this paper

KdmA, a histone H3 demethylase with bipartite function, differentially regulates primary and secondary metabolism in Aspergillus nidulans
TLDR
Agnieszka Gacek-Matthews,1# Luke M. Noble,2# Clemens Gruber,3 Harald Berger,4 Michael Sulyok,5 Ana T. Marcos,6 Joseph Strauss and Alex Andrianopoulos are co-authors on this paper.
Cell Viability Cellular Histone Acetylation but Not Kinetic Rate Constants Correlate with Histone Deacetylase ( HDAC ) Inhibitor Cell Biology :
Kaminker, Christopher E. Heise and Pascal Koth, Patrick J. Lupardus, Joshua S. Modrusan, Lars Neumann, Christopher M. Daniel F. Ortwine, Janet Gunzner, Zora Grazyna Fedorowicz, Roxanne Vallero,
Structure and Flexibility of the Yeast NuA4 Histone Acetyltransferase Complex
TLDR
Using nucleosome binding assays, the data suggests a model in which Tra1 recruits NuA4 to specific genomic sites then allowing the flexible HAT and TINTIN modules to select nearby nucleosomes for acetylation.
Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation
TLDR
Functional interactions of a writer-eraser duo, KMT2A and KDM5C, which are responsible for Wiedemann-Steiner Syndrome (WDSTS), and mental retardation X-linked syndromic Claes-Jensen type (MRXSCJ), are shown, providing a proof of principle for balancing a single writer- eraser pair to ameliorate their associated disorders.
A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
The methyltransferase activity of the trithorax group (TrxG) protein MLL1 found within its COMPASS (complex associated with SET1)-like complex is allosterically regulated by a four-subunit complex
Amelioration of Brain Histone Methylopathies by Balancing a Writer-Eraser Duo KMT2A-KDM5C
TLDR
This study uncovers common yet mutually-suppressive aspects of WDSTS and MRXCJ and provides a proof of principle for balancing a single writer-eraser pair to ameliorate their associated disorders.
Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases
TLDR
This Review aims to point out the existing confusion in the nomenclature of the human and mouse MLL gene family, to explain its historical background, and to promote an unequivocal nomenClature system for chromatin‐modifying enzymes as proposed by Allis et al. (2007).
Role of yeast JmjC-domain containing histone demethylases in actively transcribed regions.
Cell cycle-dependent chromatin shuttling of HBO1–JADE1 histone acetyl transferase (HAT) complex
TLDR
In mouse kidneys, JADE1S transiently accumulated in the cytoplasm of tubular epithelial cells during kidney regeneration, supporting biological role of HBO1–JADE1 shuttling during organ regeneration.
...
...