New Methods in Cardiovascular Biology Noise-Free Visualization of Microscopic Calcium Signaling by Pixel-Wise Fitting


Rationale: Our insights into physiological and pathophysiological cardiac excitation-contraction coupling has greatly benefited from significant advancement in optical technologies such as high-speed confocal microscopy. This has pushed pixel dwell times into the time domain of nanoseconds, resulting in low signal-to-noise ratios, which have limited data… (More)


6 Figures and Tables