# New Metabolic Lung Simulator: Development, Description, and Validation

@article{Rosenbaum2006NewML,
title={New Metabolic Lung Simulator: Development, Description, and Validation},
author={Abraham Rosenbaum and Christopher Kirby BSc and FRCPC Peter H. Breen},
journal={Journal of Clinical Monitoring and Computing},
year={2006},
volume={21},
pages={71-82}
}
Indirect calorimetry, the determination of airway carbon dioxide elimination $$\left( {V_{CO_2 } } \right)$$ and oxygen uptake $$\left( {V_{O_2 } } \right)$$ , can be used to non-invasively detect non-steady state perturbations of gas kinetics and mirror tissue metabolism. Validation of monitoring instruments in patients is difficult because there is no standard reference measurement, a wide range of physiologic values is required, and steady state is difficult to achieve and confirm. We… CONTINUE READING