New Mechanisms of Tumor-Associated Macrophages on Promoting Tumor Progression: Recent Research Advances and Potential Targets for Tumor Immunotherapy

@inproceedings{Guo2016NewMO,
  title={New Mechanisms of Tumor-Associated Macrophages on Promoting Tumor Progression: Recent Research Advances and Potential Targets for Tumor Immunotherapy},
  author={Qiujun Guo and Zhichao Jin and Yuan Yuan and Rui Liu and Tao Xu and Huamin Wei and Xinyao Xu and Shulin He and Shuntai Chen and Zhan Shi and Wei Hou and Baojin Hua},
  booktitle={Journal of immunology research},
  year={2016}
}
The majority of basic and clinical studies have shown a protumor function of tumor-associated macrophages (TAMs), which represent a large proportion of matrix cells. TAMs promote tumorigenesis, and their number is related to the malignancy degree and poor prognosis of many kinds of tumors. Macrophage plasticity makes it possible to change the tumor microenvironment and remodel antitumor immunity during cancer immunotherapy. Increasing numbers of studies have revealed the effects of TAMs on the… CONTINUE READING