New Lignans and Iridoid Glycosides from Dipsacus asper Wall.

  title={New Lignans and Iridoid Glycosides from Dipsacus asper Wall.},
  author={Xin-guang Sun and Guoxu Ma and Dawei Zhang and Wenhua Huang and Gang Ding and Huagang Hu and Guangzhong Tu and Baolin Guo},
  volume={20 2},
Six new compounds, including four new lignans, dipsalignan A (1), B-D (3-5), and two new bis-iridoid glycoside dimmers, dipsanosides M (7) and N (8), together with two known compounds (2) and (6), have been isolated from the roots of Dipsacus asper Wall. Their structures were established on the basis of spectroscopic data (MS, 1D, 2D NMR, and CD) and chemical methods. All the isolated compounds were tested against human immunodeficiency virus-1 (HIV-1) integrase inhibition activities, and only… CONTINUE READING
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