New Insights into the Steen Solution Properties: Breakthrough in Antioxidant Effects via NOX2 Downregulation

@inproceedings{Carnevale2014NewII,
  title={New Insights into the Steen Solution Properties: Breakthrough in Antioxidant Effects via NOX2 Downregulation},
  author={Roberto Carnevale and Giuseppe G. L. Biondi-Zoccai and Mariangela Peruzzi and Elena De Falco and Isotta Chimenti and Federico Venuta and Marco Anile and Daniele Diso and Elena Cavarretta and Antonino G. M. Marullo and Patrizio Sartini and Pasquale Pignatelli and Francesco Violi and Giacomo Frati},
  booktitle={Oxidative medicine and cellular longevity},
  year={2014}
}
Ex vivo lung perfusion (EVLP) allows perfusion and reconditioning of retrieved lungs for organ transplantation. The Steen solution is specifically designed for this procedure but the mechanism through which it elicits its activity is still to be fully clarified. We speculated that Steen solution may encompass antioxidant properties allowing a reestablishment of pulmonary tissue homeostasis. Blood samples from 10 healthy volunteers were recruited. Platelets and white cells were incubated with… CONTINUE READING