New Insights into the Functions of Transcription Factors that Bind the RNA Polymerase Secondary Channel

@inproceedings{Zenkin2015NewII,
  title={New Insights into the Functions of Transcription Factors that Bind the RNA Polymerase Secondary Channel},
  author={Nikolay Zenkin and Yulia Yuzenkova and Sivaramesh Wigneshweraraj and Deborah Meetze Hinton},
  booktitle={Biomolecules},
  year={2015}
}
Transcription elongation is regulated at several different levels, including control by various accessory transcription elongation factors. A distinct group of these factors interacts with the RNA polymerase secondary channel, an opening at the enzyme surface that leads to its active center. Despite investigation for several years, the activities and in vivo roles of some of these factors remain obscure. Here, we review the recent progress in understanding the functions of the secondary channel… CONTINUE READING
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