New Insights into the Androgen-Targeted Therapies and Epigenetic Therapies in Prostate Cancer

@inproceedings{Godbole2011NewII,
  title={New Insights into the Androgen-Targeted Therapies and Epigenetic Therapies in Prostate Cancer},
  author={Abhijit M. Godbole and Vincent C. O. Njar},
  booktitle={Prostate cancer},
  year={2011}
}
Prostate cancer is the most common cancer in men in the United States, and it is the second leading cause of cancer-related death in American men. The androgen receptor (AR), a receptor of nuclear family and a transcription factor, is the most important target in this disease. While most efforts in the clinic are currently directed at lowering levels of androgens that activate AR, resistance to androgen deprivation eventually develops. Most prostate cancer deaths are attributable to this… CONTINUE READING