New Insight into an Old Concept: Role of Immature Erythroid Cells in Immune Pathogenesis of Neonatal Infection

@inproceedings{Elahi2014NewII,
  title={New Insight into an Old Concept: Role of Immature Erythroid Cells in Immune Pathogenesis of Neonatal Infection},
  author={Shokrollah Elahi},
  booktitle={Front. Immunol.},
  year={2014}
}
Newborns are exceedingly susceptible to infection. However, very little is known about what governs the immunological differences seen in early life that result in extreme vulnerability to infection, nor how this changes during infancy. Herein, I provide evidence that the reduced ability to mount a protective immune response to pathogens is not due to an inherent immaturity of neonatal immune cells but instead the functions of these immune cells are actively suppressed by CD71(+) erythroid… CONTINUE READING