New Dual Mode Gadolinium Nanoparticle Contrast Agent for Magnetic Resonance Imaging

@inproceedings{Ghaghada2009NewDM,
  title={New Dual Mode Gadolinium Nanoparticle Contrast Agent for Magnetic Resonance Imaging},
  author={Ketan B. Ghaghada and Murali K Ravoori and Divya Sabapathy and James A Bankson and Vikas Kundra and Ananth Annapragada},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND Liposomal-based gadolinium (Gd) nanoparticles have elicited significant interest for use as blood pool and molecular magnetic resonance imaging (MRI) contrast agents. Previous generations of liposomal MR agents contained gadolinium-chelates either within the interior of liposomes (core-encapsulated gadolinium liposomes) or presented on the surface of liposomes (surface-conjugated gadolinium liposomes). We hypothesized that a liposomal agent that contained both core-encapsulated… CONTINUE READING
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