New Determinant for the CaVβ2 Subunit Modulation of the CaV1.2 Calcium Channel*

@article{Lao2008NewDF,
  title={New Determinant for the CaV$\beta$2 Subunit Modulation of the CaV1.2 Calcium Channel*},
  author={Q. Lao and E. Kobrinsky and J. Harry and A. Ravindran and N. Soldatov},
  journal={Journal of Biological Chemistry},
  year={2008},
  volume={283},
  pages={15577 - 15588}
}
Cavβ subunits support voltage gating of Cav1.2 calcium channels and play important role in excitation-contraction coupling. The common central membrane-associated guanylate kinase (MAGUK) region of Cavβ binds to the α-interaction domain (AID) and the IQ motif of the pore-forming α1C subunit, but these two interactions do not explain why the cardiac Cavβ2 subunit splice variants differentially modulate inactivation of Ca2+ currents (ICa). Previously we described β2Δg, a functionally active… Expand
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References

SHOWING 1-10 OF 39 REFERENCES
Essential Cavβ modulatory properties are AID-independent
Unique regulatory properties of the type 2a Ca2+ channel beta subunit caused by palmitoylation.
...
1
2
3
4
...