New Derivative and Differential Spectrophotometric Methods for the Determination of Pterostilbene-An Antioxidant

@article{Annapurna2015NewDA,
  title={New Derivative and Differential Spectrophotometric Methods for the Determination of Pterostilbene-An Antioxidant},
  author={Mukthinuthalapati Mathrusri Annapurna and Josyula Sai Phani Kumar},
  journal={Pharmaceutical methods},
  year={2015},
  volume={6},
  pages={143-147}
}
Pterostilbene found in blueberries and Pterocarpus marsupium heartwood is structurally similar to resveratrol. It is used for the treatment of cancer, diabetes and fungal infections. Three spectrophotometric methods have been developed for the determination of Pterostilbene. Two first derivative methods and one difference spectrophotometric method were attempted. Two first derivative spectroscopic methods were developed in sodium hydroxide (Method A) and methanol (Method B) and differential… Expand
2 Citations

Figures and Tables from this paper

Development of a Validated Stability Indicating Liquid Chromatographic Method for the Determination of Pterostilbene
TLDR
The drug was found to be sensitive towards acidic and alkaline stress conditions and the proposed stability-indicating liquid chromatographic method is selective, specific, robust and can be applied for the assay of pharmaceutical dosage forms. Expand
Rapid, Sensitive, and Sustainable Reversed-Phase HPTLC Method in Comparison to the Normal-Phase HPTLC for the Determination of Pterostilbene in Capsule Dosage Form
The greenness evaluation of literature analytical methods for pterostilbene (PT) analysis was not performed. Accordingly, the rapid, sensitive, and green/sustainable reversed-phase high-performanceExpand

References

SHOWING 1-10 OF 20 REFERENCES
High-performance liquid chromatographic analysis of pterostilbene in biological fluids using fluorescence detection.
TLDR
A novel and simple high-performance liquid chromatographic method was developed and applied to the study of pterostilbene pharmacokinetics in rats, which successfully determined its concentration in foodstuffs. Expand
Determination of pterostilbene in rat plasma by a simple HPLC-UV method and its application in pre-clinical pharmacokinetic study.
TLDR
A simple HPLC-UV method was developed and validated for the quantification of pterostilbene, a pharmacologically active phytoalexin in rat plasma and appeared to have better pharmacokinetic characteristics than its natural occurring analog, resveratrol. Expand
RP - HPLC Studies on Quantitative Determination of Pterostilbene in Dragon's Blood
Objective: To establish a HPLC method for the separation and determination of pterostilbene in Drag-on's Blood. Methods: Using Phenomenex C18 reverse phase column (250 mm × 4. 6 mm, 5 μm) andExpand
Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol.
TLDR
Pterostilbene was shown to be as effective as resveratrol in inhibiting electrolyte leakage caused by herbicide-induced oxidative damage, and both compounds had the same activity as alpha-tocopherol. Expand
Antioxidant activity of hydroxystilbene derivatives in homogeneous solution.
TLDR
A comparison of these results with previously reported data on the proapoptotic activity of these stilbenoids suggests that these two properties are not correlated. Expand
Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India.
TLDR
HPLC analysis of this age old formulation of darakchasava revealed the presence of polyphenols like resveratrol and pterostilbene, now known as antioxidants, cancer chemopreventive agents, and also known to reduce mortality from coronary heart disease by increasing high density lipoproteins like cholesterol and inhibiting platelet aggregation. Expand
Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma.
TLDR
The association of PTER and QUER inhibits metastatic melanoma growth and extends host survival and the anti-metastatic mechanism involves a PTER-induced inhibition of vascular adhesion molecule 1 expression in the hepatic sinusoidal endothelium, which consequently decreases B16M-F10 cell adhesion to the endothelia through very late activation antigen 4. Expand
Specific Structural Determinants Are Responsible for the Antioxidant Activity and the Cell Cycle Effects of Resveratrol*
TLDR
The results showed that the hydroxyl group in 4′ position is not the sole determinant for antioxidant activity, and the presence of 4′-OH together with stereoisomery in the trans-conformation was absolutely required for inhibition of cell proliferation. Expand
Resveratrol, pterostilbene, and piceatannol in vaccinium berries.
TLDR
These naturally occurring stilbenes, known to be strong antioxidants and to have cancer chemopreventive activities, will add to the purported health benefits derived from the consumption of these small fruits. Expand
Confirmation towards establishing antidiabetic activity in heart wood of Pterocarpus marsupium and analysis of phytoconstituents
The crude powder, ethanolic extract and aqueous, chloroform, hexane and n-butanol soluble fractions of ethanolic extract of heart wood of Pterocarpus marsupium (Family: Fabaceae) showed markedExpand
...
1
2
...