New Definition for the Partial Remission Period in Children and Adolescents With Type 1 Diabetes

@inproceedings{Mortensen2009NewDF,
  title={New Definition for the Partial Remission Period in Children and Adolescents With Type 1 Diabetes},
  author={Henrik Bindesb\ol Mortensen and Philip Hougaard and P. Swift and Lars Folmer Hansen and Reinhard W. Holl and Hilary Hoey and Hilde Bjoerndalen and Carine E de Beaufort and Francesco G Chiarelli and Thomas Danne and Eugen J. Schoenle and Jan {\AA}man},
  booktitle={Diabetes care},
  year={2009}
}
OBJECTIVE To find a simple definition of partial remission in type 1 diabetes that reflects both residual beta-cell function and efficacy of insulin treatment. RESEARCH DESIGN AND METHODS A total of 275 patients aged <16 years were followed from onset of type 1 diabetes. After 1, 6, and 12 months, stimulated C-peptide during a challenge was used as a measure of residual beta-cell function. RESULTS By multiple regression analysis, a negative association between stimulated C-peptide and A1C… CONTINUE READING
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