New DNA polymorphisms of human MMH/OGG1 gene: prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.

@article{Ishida1999NewDP,
  title={New DNA polymorphisms of human MMH/OGG1 gene: prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.},
  author={Tadashi Ishida and Riou Takashima and Masashi Fukayama and Chuya Hamada and Yoshitaka Hippo and Toshiyuki Fujii and Satoru Moriyama and Chikako Matsuba and Yutaka Nakahori and Hiroyuki Morita and Yoshio Yazaki and Tetsuro Kodama and Shin-ichiro Nishimura and Hiroyuki Aburatani},
  journal={International journal of cancer},
  year={1999},
  volume={80 1},
  pages={18-21}
}
MMH/OGG1 is an 8-hydroxyguanine-specific DNA glycosylase/AP-lyase, one of the mutator enzymes for the excision repair of 8-hydroxyguanine. DNA polymorphisms in human MMH/OGG1 gene were newly identified and analyzed to examine a possible association with lung-cancer risk by a population-based study. Polymorphic allele 3 in hMMH/OGG1 exon 1 was significantly prevalent among Japanese patients with adenocarcinoma of the lung [odds ratio (OR): 3.152, 95% confidence interval (CI): 1.266-7.845… CONTINUE READING

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8-Hydroxyguanine: From its discovery in 1983 to the present status

Proceedings of the Japan Academy. Series B, Physical and biological sciences • 2006

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