New Cytogenetic Aspects of Myelodysplasia and Acute Leukemia

@inproceedings{Mamaev1992NewCA,
  title={New Cytogenetic Aspects of Myelodysplasia and Acute Leukemia},
  author={Nikolay N. Mamaev and Valerija A. Pavlova and Olesja Marinets},
  year={1992}
}
The use of modern chromosomal banding techniques in preleukemia and leukemia has revealed the presence of nonran-dom chromosome abnormalities, some of which have clear diagnostic and prognostic significance. Among these are translocations t(8;21), t(15;17), t(9;ll), t(4;ll), t(8;14), t(9;22); trisomies 4, 8, 12, 21, 1q; monosomies 5, 7, X, Y; deletions 5q-, 7q-, 9q-, 12p-, 20 q- and some others [4]. According to our data nonrandom chromosome abnormalities were revealed in 35 of 47 patients (70… CONTINUE READING
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