Optimizing Isotretinoin Treatment of Acne: Update on Current Recommendations for Monitoring, Dosing, Safety, Adverse Effects, Compliance, and Outcomes
- MedicineAmerican Journal of Clinical Dermatology
The article outlines the advantages and disadvantages of standard, high-dose, and low-dose isotretinoin regimens; discusses the current status of controversies surrounding isot retinoin (including depression/suicide, pregnancy, and inflammatory bowel disease); reviews monitoring recommendations and treatment for hypertriglyceridemia and elevated transaminase levels; and discusses common adverse effects seen with isotretin, along with their treatment and prevention.
Oral isotretinoin for acne: a complete overview
- MedicineExpert opinion on drug safety
Oral isotretinoin represents a valid therapeutic alternative in treating severe and mild-to-moderate acne lesions, also reducing scarring damage, and should be considered in order to obtain optimal results.
Acne: What primary care providers need to know.
- MedicineThe Nurse practitioner
The pathophysiology of acne is outlined and effective treatment options are outlined, including laser and light therapy, topical products, oral medications, or a combination of these options.
Fighting acne for the fighting forces.
A case in which the pulsed dye laser (PDL) was successfully used to treat inflammatory acne in an active-duty servicemember is presented to highlight the use of PDL as an available and effective treatment option for acne in this population.
A severe inflammatory acne was successfully cleared by topical photodynamic therapy mediated with 5-aminolevulinic acid in an refractory aplastic anemia female patient: a case report
- MedicineWorld Congress of the International Photodynamic Association
A 24-year-old female suffered from refractory aplastic anemia for 10 years and presented pustules, nodules and inflammatory sinus tract with pus on her face and trunk 5 months after took Stanozolol, and needed autologous stem cell transplantation.
Antibiotic Resistance Risk with Oral Tetracycline Treatment of Acne Vulgaris
A novel narrow-spectrum tetracycline, sarecycline, was approved to treat moderate-to-severe acne vulgaris in patients 9-years-old and above in 2018 and was designed to target Cutibacterium acnes, the pathogenic bacterium in acne vulgar is, which may reduce the risk of resistance.
Acne vulgar: aspectos gerais e atualizações no protocolo de tratamento
A bibliographic search was carried out including articles and reviews with the theme “acne vulgaris” in the databases Pubmed, Medline, Scopus and Web of Science finding a significant improvement in acne with the use of antibiotics, probiotics and prebiotics for regulation of the skin microbiome.
Identifying gaps and providing recommendations to address shortcomings in the investigation of acne sequelae by the Personalising Acne: Consensus of Experts panel
- MedicineJAAD international
Keloid pathophysiology: fibroblast or inflammatory disorders?
- MedicineJPRAS open
Topical Preparations and Prescription Medications in Aesthetics
- MedicineAesthetic Procedures: Nurse Practitioner's Guide to Cosmetic Dermatology
A variety of preparations, absorption properties and effect on the skin, certain ingredients, and intended result will be discussed in this chapter.
SHOWING 1-10 OF 65 REFERENCES
Creatine phosphokinase values during isotretinoin treatment for acne
- MedicineInternational journal of dermatology
The aim of this study was to investigate the incidence, course, and clinical significance of severe hyperphosphokinasemia in isotretinoin therapy for acne.
Non-antibiotic Isotretinoin Treatment Differentially Controls Propionibacterium acnes on Skin of Acne Patients
- Medicine, BiologyFront. Microbiol.
The role of tetracycline’s and macrolides, which are currently first line treatments in dermatology, might be reserved for severe or life-threatening infections since current antibiotic stewardship guidelines from medical departments no longer prescribe these antibiotics for routine use.
[Muscular damage during isotretinoin treatment].
- MedicineAnnales de dermatologie et de venereologie
The benign nature of the muscle effect appears to be validated although there were some patients who had persistent and/or severe signs, probably because they systematically looked for them.
Antibiotics and acne: an emerging iceberg of antibiotic resistance?
- Medicine, BiologyThe British journal of dermatology
The issue of inappropriate antibiotic prescribing for acne in the U.K. is highlighted, demonstrating that among recent referrals to secondary care, the mean duration of antibiotic use was 305 days, in concordance with a wider European pattern.
Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin
- MedicineInternational Journal of Legal Medicine
The case of a 20-year-old male who died from severe generalised rhabdomyolysis associated with isotretinoin treatment is presented.
Scarred for life?
Acne vulgaris is a common inflammatory dermatosis capable of producing significant psychological and physical scarring. The following work describes the benefit of using a questionnaire as a clinical…
Topical retinoic acid in the treatment of fine acne scarring
- MedicineThe British journal of dermatology
A patient in whom the daily application of tretinoin 0'05% resulted in a marked improvement in the superficial scarring secondary to acne vulgaris is reported, report SIR.SIR.
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
- MedicineJournal of the American Academy of Dermatology
The efficacy and safety of non‐pharmacological therapies for the treatment of acne vulgaris: A systematic review and best‐evidence synthesis
- Biology, MedicineJournal of the European Academy of Dermatology and Venereology : JEADV
Non‐pharmacological therapies can be viable alternatives for conventional therapies, however, sufficient evidence‐based support in the efficacy and safety of non‐pharmological therapies is lacking.
Clinical significance of markedly elevated serum creatine kinase levels in patients with acne on isotretinoin.
- Medicine, BiologyActa dermato-venereologica
In conclusion, marked hyperCKemia with or without muscle-related complaints in isotretinoin-treated patients with acne is a benign phenomenon.