New Clinical Subtypes of Parkinson Disease and Their Longitudinal Progression: A Prospective Cohort Comparison With Other Phenotypes.

@article{Fereshtehnejad2015NewCS,
  title={New Clinical Subtypes of Parkinson Disease and Their Longitudinal Progression: A Prospective Cohort Comparison With Other Phenotypes.},
  author={Seyed-Mohammad Fereshtehnejad and Silvia Rios Romenets and Julius B M Anang and V{\'e}ronique Latreille and J F Gagnon and Ronald B. Postuma},
  journal={JAMA neurology},
  year={2015},
  volume={72 8},
  pages={863-73}
}
IMPORTANCE There is increasing evidence that Parkinson disease (PD) is heterogeneous in its clinical presentation and prognosis. Defining subtypes of PD is needed to better understand underlying mechanisms, predict disease course, and eventually design more efficient personalized management strategies. OBJECTIVES To identify clinical subtypes of PD, compare the prognosis and progression rate between PD phenotypes, and compare the ability to predict prognosis in our subtypes and those from… CONTINUE READING