New Cardiovascular and Pulmonary Therapeutic Strategies Based on the Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas Receptor Axis

@inproceedings{Ferreira2012NewCA,
  title={New Cardiovascular and Pulmonary Therapeutic Strategies Based on the Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas Receptor Axis},
  author={Anderson Jos{\'e} Ferreira and Tatiane Mois{\'e}s Murça and Rodrigo A Fraga-Silva and Carlos Henrique Cunha De Castro and Mohan K. Raizada and Robson Santos},
  booktitle={International journal of hypertension},
  year={2012}
}
Angiotensin (Ang)-(1-7) is now recognized as a biologically active component of the renin-angiotensin system (RAS). The discovery of the angiotensin-converting enzyme homologue ACE2 revealed important metabolic pathways involved in the Ang-(1-7) synthesis. This enzyme can form Ang-(1-7) from Ang II or less efficiently through hydrolysis of Ang I to Ang-(1-9… CONTINUE READING