New Caledonia: A ‘ Hot Spot’ for Valuable Chemodiversity

  title={New Caledonia: A ‘ Hot Spot’ for Valuable Chemodiversity},
  author={Paul Coulerie and Cyril Poullain},
  journal={Chemistry \& Biodiversity},
The flora of New Caledonia encompasses more than 3000 plant species and almost 80% are endemic. New Caledonia is considered as a ‘hot spot’ for biodiversity. With the current global loss of biodiversity and the fact that several drugs and pesticides become obsolete, there is an urgent need to increase sampling and research on new natural products. In this context, we review the chemical knowledge available on New Caledonian native flora from economical perspectives. We expect that a better… Expand
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New Caledonia: A Hot Spot for Valuable Chemodiversity Part 3: Santalales, Caryophyllales, and Asterids
It is shown that the high rate of endemism is correlated with the originality of phytochemicals encountered in New Caledonian plants, and several groups, such as Sapotaceae, that are unexplored in NewCaledonia despite the high chemical interest in them are considered to have priority in future chemical investigations. Expand
New Caledonia: A “Hot Spot” for Valuable Chemodiversity. Part 2. Basal Angiosperms and Eudicot Rosids
HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching andExpand


New Caledonia: A ‘Hot Spot’ for Valuable Chemodiversity. Part 1: Gymnosperms
The chemical information available on New Caledonian native flora from economical perspectives is reviewed to expect that a better knowledge of the economic potential will encourage the plantation of native plants for the development of a sustainable economy which will participate in the conservation of biodiversity. Expand
Natural‐Product Diversity of the New Caledonian Marine Ecosystem Compared to Other Ecosystems: A Pharmacologically Oriented View
In comparison with other ecosystems, biodiversity and natural‐product diversity of the New Caledonian marine ecosystem, comprising lagoons, barrier reefs, and deep waters in seamount regions, areExpand
Screening of 50 Cunoniaceae species from New Caledonia for antimicrobial properties
Cunonia macrophylla appears to be the best candidate for a chemical investigation using bioguided fractionation as extracts from its leaves and flowers effectively inhibited six strains (one yeast, two Gram ‐ve bacteria and three Gram +ve bacteria). Expand
New cytotoxic guttiferone analogues from Garcinia virgata from New Caledonia.
The structures of these benzophenones were mainly elucidated using 1D and 2D NMR spectroscopy and were weakly cytotoxic on the KB cell line with IC50 values of 4.70 and 5.0 microg/mL respectively. Expand
Bioactive ellagitannins from Cunonia macrophylla, an endemic Cunoniaceae from New Caledonia.
Antimicrobial effects on bacterial human pathogens and on a plant pathogen as well as on a human pathogenic yeast were investigated and inhibitory effects of all molecules against xanthine oxidase in relation to their structure was evaluated and compared. Expand
Quassinoid Bitter Principles.
  • J. Polonsky
  • Chemistry, Medicine
  • Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles
  • 1973
The Simaroubaceae form a large botanical family of mostly pantropical distribution; only a few representatives (such as Ailanthus) extend into temperate regions and many new bitter constituents have been isolated and had their structures elucidated. Expand
Annonaceae: bio-resource for tomorrow's drug discovery
Members of the Annonaceae have the particularity to elaborate a broad spectrum of natural products that have displayed anti-bacterial, anti-fungal, and anti-protozoal effects and have been used for the treatment of medical conditions, such as skin diseases, intestinal worms, inflammation of the eyes, HIV, and cancer. Expand
The genus Stephania (Menispermaceae): chemical and pharmacological perspectives.
This review presents comprehensive information on the chemistry and pharmacology of the genus Stephania together with the traditional uses of many of its plants and the structure-activity relationship of different compounds. Expand
An examination of the leaf essential oils of three Eugenia (Myrtaceae) species endemic to New Caledonia
The leaf essential oils of three Eugenia species, E. gacognei Montrouz., E. horizontalis Pancher ex Brongn. & Gris and E. noumeensis Guillaumin, have been examined. Eugenia gacognei was a variableExpand
Cytotoxic turrianes of Kermadecia elliptica from the New Caledonian rainforest.
A LC/APCI-MS study performed on kermadecins A, B and C provided a reliable method for the detection of other analogues existing in small quantities in the extract, which led to the isolation of five other members of this chemical series. Expand