Effect of Various Injection Speeds of Propofol on Blood Pressure, Time Taken and Dose Required for Induction of Anesthesia: A Prospective Observational Study
At faster speeds of injection of Propofol, larger doses are required for induction of anesthesia and significant drop in systolic, diastolic and mean arterial pressures while as the time taken for induction of anesthesia was shorter when compared to the injection at slower speeds.
The effect of propofol when injected at different speeds for induction of general anesthesia: an observational study
Induction dose required for loss of consciousness increased with a faster rate of infusion while time for induction was shorter in P800 compared to P400 and P600, and the decrease in mean blood pressure was less after induction in P400.
Effect of propofol titration v/s bolus during induction of anesthesia on hemodynamics and bispectral index.
- Medicine, BiologyMiddle East journal of anaesthesiology
Titration of Propofol reduces hemodynamic changes, dose requirement and is able to achieve same level of BIS as in bolus as well as reducing the dose requirement.