New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities.

Abstract

CXCR4 is a target of growing interest for the development of new therapeutic drugs and imaging agents as its role in multiple disease states has been demonstrated. AMD3100, a CXCR4 chemokine receptor antagonist that is in current clinical use as a haematopoietic stem cell mobilising drug, has been widely studied for its anti-HIV properties, potential to… (More)
DOI: 10.1039/c4dt02972k

Topics

6 Figures and Tables

Statistics

0100200201520162017
Citations per Year

Citation Velocity: 18

Averaging 18 citations per year over the last 3 years.

Learn more about how we calculate this metric in our FAQ.

Cite this paper

@article{Poty2015NewAD, title={New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities.}, author={Sophie Poty and Pauline D{\'e}sog{\`e}re and Christine Goze and Fr{\'e}d{\'e}ric Boschetti and Thomas D'huys and Dominique Schols and Christopher Cawthorne and Stephen J. Archibald and Helmut R Ma{\"e}cke and Franck Denat}, journal={Dalton transactions}, year={2015}, volume={44 11}, pages={5004-16} }