New 6-substituted bile acids: physico-chemical and biological properties of 6 alpha-methyl ursodeoxycholic acid and 6 alpha-methyl-7-epicholic acid.

Abstract

New analogs of ursodeoxycholic acid and 7-epicholic acid containing a 6 alpha-methyl group were synthesized, and their physico-chemical properties were studied and compared with those of their natural analogs. The 6 alpha-methyl group slightly increases the lipophilicity and slightly lowers the critical micellar concentration with respect to the… (More)

Topics

Cite this paper

@article{Roda1994New6B, title={New 6-substituted bile acids: physico-chemical and biological properties of 6 alpha-methyl ursodeoxycholic acid and 6 alpha-methyl-7-epicholic acid.}, author={A. L. Roda and Roberto Pellicciari and C Cerr{\'e} and Carla Polimeni and Bahman M Sadeghpour and Maura Marinozzi and Gianni Forti and Ester Sapigni}, journal={Journal of lipid research}, year={1994}, volume={35 12}, pages={2268-79} }