Never-resting microglia: physiological roles in the healthy brain and pathological implications

Abstract

Microglia are the resident macrophages of the central nervous system (CNS), largely known as the major orchestrators of the immune response. As such, they have been traditionally studied in various contexts of trauma, injury and disease, where their phenotypic transformation (or “activation”) has been assumed to induce a wide range of mostly detrimental… (More)
DOI: 10.3389/fncel.2014.00240

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