Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology.

Abstract

Sickle cell disease (SCD) is a severe genetic blood disorder characterized by hemolytic anemia, episodic vaso-occlusion, and progressive organ damage. Current management of the disease remains symptomatic or preventative. Specific treatment targeting major complications such as vaso-occlusion is still lacking. Recent studies have identified various cellular… (More)
DOI: 10.1182/blood-2015-09-618538

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Cite this paper

@article{Zhang2016NeutrophilsPA, title={Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology.}, author={Dachuan Zhang and Chunliang Xu and Deepa G Manwani and Paul S Frenette}, journal={Blood}, year={2016}, volume={127 7}, pages={801-9} }