Neutrophils induce damage to respiratory epithelial cells infected with respiratory syncytial virus.

@article{Wang1998NeutrophilsID,
  title={Neutrophils induce damage to respiratory epithelial cells infected with respiratory syncytial virus.},
  author={S Z Wang and Haiming Xu and Andrea Wraith and Jeffrey J. Bowden and John H. Alpers and Kevin D Forsyth},
  journal={The European respiratory journal},
  year={1998},
  volume={12 3},
  pages={612-8}
}
The mechanisms by which respiratory syncytial virus (RSV) infection induces bronchiolitis and airway disease are unclear. The presence of large numbers of polymorphonuclear leukocytes (PMN) in the airways of infants with RSV infection suggests a potential role of PMN in airway injury associated with RSV infection. To investigate the potential role of neutrophils in RSV bronchiolitis, human alveolar type II cells (A549 cells) were infected with different doses of RSV for 6-48 h. A 51Cr-releasing… CONTINUE READING

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