Neutrophils contribute to fracture healing by synthesizing fibronectin+ extracellular matrix rapidly after injury.

Abstract

The role of inflammatory cells in bone regeneration remains unclear. We hypothesize that leukocytes contribute to fracture healing by rapidly synthesizing an "emergency extracellular matrix (ECM)" before stromal cells infiltrate the fracture hematoma (FH) and synthesize the eventual collagenous bone tissue. 53 human FHs were isolated at different time… (More)
DOI: 10.1016/j.clim.2016.02.001

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