Neutrophils as active regulators of the immune system in the tumor microenvironment.

@article{Shaul2017NeutrophilsAA,
  title={Neutrophils as active regulators of the immune system in the tumor microenvironment.},
  author={Merav E Shaul and Zvi Gregory Fridlender},
  journal={Journal of leukocyte biology},
  year={2017},
  volume={102 2},
  pages={
          343-349
        }
}
In recent years, the role of immune cells in tumor progression has been a matter of increasing interest. Neutrophils constitute an important portion of the immune cells infiltrating the tumor microenvironment. Traditionally viewed as the first line of defense against infections, it is now well accepted that neutrophils also have an important role in multiple aspects of cancer biology. Multiple and heterogeneous neutrophil subsets have been identified in tumors and in circulation. Evidence from… CONTINUE READING