Neutrophils are not required for resolution of acute gouty arthritis in mice

To the Editor: Gout is triggered when the deposition of monosodium urate (MSU) crystals in joints induces acute inflammation characterized by the recruitment of neutrophils1,2. Attacks of gout resolve in days, despite the persistence of crystals in structures called tophi, but the mechanisms that underlie this rapid resolution of inflammation are unknown1,3… CONTINUE READING