Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice.

@article{Rogers1993NeutrophilsAI,
  title={Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice.},
  author={H W Rogers and Emil R Unanue},
  journal={Infection and immunity},
  year={1993},
  volume={61 12},
  pages={
          5090-6
        }
}
The importance of neutrophils in killing extracellular, pyogenic bacteria has long been established. However, there is only indirect evidence for a role for neutrophils in resistance against intracellular organisms. In this study, we directly demonstrate the involvement of neutrophils in defense against Listeria monocytogenes in normal C.B-17 immunocompetent and C.B-17 SCID mice. Because of the lack of sterilizing T-cell immunity, SCID mice are unable to completely eliminate listeriae… CONTINUE READING

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