Neutrophils and macrophages cooperate in host resistance against Leishmania braziliensis infection.

@article{Novais2009NeutrophilsAM,
  title={Neutrophils and macrophages cooperate in host resistance against Leishmania braziliensis infection.},
  author={Fernanda Oliveira Novais and R{\^o}mulo Carvalho Santiago and Andr{\'e} B{\'a}fica and Ricardo Khouri and L{\'i}lian Gomes Afonso and Val{\'e}ria Matos Borges and Cl{\'a}udia Ida Brodskyn and Manoel Barral-Netto and Aldina Barral and Camila I de Oliveira},
  journal={Journal of immunology},
  year={2009},
  volume={183 12},
  pages={
          8088-98
        }
}
Neutrophils play an active role in the control of infections caused by intracellular pathogens such as Leishmania. In the present study, we investigated the effect of neutrophil depletion at the time of Leishmania braziliensis infection of BALB/c mice and how neutrophils interact with the infected macrophage to promote parasite elimination. The in vivo depletion of neutrophils led to a significant increase in parasite load and enhanced the Th1-Th2 immune response in this experimental model of… CONTINUE READING

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IFN- impairs superoxide-dependent parasite killing in human macrophages: evidence for a deleterious role of SOD1 in cutaneous leishmaniasis

R. Khouri, A. Bafica, +6 authors J. Van Weyenbergh
  • J. Immunol
  • 2009
VIEW 8 EXCERPTS
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