Neutrophilic leukocytosis in advanced stage polycythemia vera: hematopathologic features and prognostic implications


Polycythemia vera in 20–30% of cases progresses towards post-polycythemic myelofibrosis, an advanced phase characterized by decreased red blood cells counts and increasing splenomegaly with extramedullary hematopoiesis. There is evidence that the presence of neutrophilic leukocytosis at polycythemia vera disease outset is associated with an increased risk… (More)
DOI: 10.1038/modpathol.2015.100


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