Neutrophil transfusions: kinetics and functions of neutrophils mobilized with granulocyte-colony-stimulating factor and dexamethasone.

@article{Dale1998NeutrophilTK,
  title={Neutrophil transfusions: kinetics and functions of neutrophils mobilized with granulocyte-colony-stimulating factor and dexamethasone.},
  author={David C Dale and W Conrad Liles and Christine C Llewellyn and Emilie Rodger and Trevor R. P. Price},
  journal={Transfusion},
  year={1998},
  volume={38 8},
  pages={
          713-21
        }
}
BACKGROUND The collection of adequate numbers of neutrophils (polymorphonuclear leukocytes, PMNs) from normal donors has long hampered the development of neutrophil transfusion therapy. The stimulation of donors with granulocyte-colony-stimulating factor (G-CSF) plus dexamethasone is a promising way of improving PMN collections. STUDY DESIGN AND METHODS Sixteen normal subjects received G-CSF (600 micrograms subcutaneously) and dexamethasone (8 mg by mouth) 12 hours before leukapheresis… CONTINUE READING
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